Abnormalities of intrinsic functional connectivity in autism spectrum disorders,
نویسندگان
چکیده
منابع مشابه
Abnormalities of intrinsic functional connectivity in autism spectrum disorders,
Autism spectrum disorders (ASD) impact social functioning and communication, and individuals with these disorders often have restrictive and repetitive behaviors. Accumulating data indicate that ASD is associated with alterations of neural circuitry. Functional MRI (FMRI) studies have focused on connectivity in the context of psychological tasks. However, even in the absence of a task, the brai...
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Ongoing debate exists within the resting-state functional MRI (fMRI) literature over how intrinsic connectivity is altered in the autistic brain, with reports of general over-connectivity, under-connectivity, and/or a combination of both. Classifying autism using brain connectivity is complicated by the heterogeneous nature of the condition, allowing for the possibility of widely variable conne...
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OBJECTIVE Connectivity atypicalities in autism spectrum disorders (ASD) have been extensively proposed. The default mode network (DMN) is critical in this study, given the insight it provides for long-distance connectivity, and the importance of regions in this network for introspection and social emotion processing, areas affected in ASD. However, study of this network has largely been limited...
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Secondary to clinical features indicating chronic inflammation and immune dysregulation, the immune system has long been suspected to have a role in autism spectrum disorders (ASD). Studies of postmortem autistic brains indicate the presence of immune mediated chronic inflammation in some but not all autistic brains. However, studies of immune abnormalities in ASD children yielded no conclusive...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2009
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2009.04.069